Nutrition and Healing
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I’ve talked a lot about antibiotic resistance before—but it’s an issue that keeps rearing its head in troubling new ways.

And the latest threat is one you might not have thought about in decades: typhoid fever.

While typhoid fever is rare in the U.S. today, it’s not gone.

Globally, it remains a serious—and growing—concern. And now, the bacterium behind this ancient disease is becoming immune to the very drugs we’ve relied on to treat it.

For seniors, who are already more vulnerable to infections, this isn’t just another far-off health crisis. It’s a pressing issue with implications right here at home.

Why Typhoid Deserves Your Attention

Typhoid fever is caused by a bacterium called Salmonella enterica serovar Typhi (S. Typhi). Symptoms include prolonged fever, weakness, abdominal pain, and in severe cases, life-threatening complications.

Here’s what’s alarming: Antibiotics have long been the go-to treatment. But S. Typhi is rapidly evolving to outsmart them.

A newer form, known as extensively drug-resistant (XDR) typhoid, has already been found in nearly 200 cases outside its usual hotspots in South Asia.

And the bacteria are spreading globally, from Southeast Asia to Africa… and even the U.S.

The last remaining effective oral antibiotic, azithromycin, may not work for much longer.

Without new treatments, typhoid could become untreatable in the future.

What Can You Do?

This all sounds dire—but there’s good news. Prevention works, and we know what steps to take to protect ourselves.

Here’s what you can do:

  1. Stay Vaccinated. While typhoid vaccines are typically recommended for international travelers heading to endemic areas, they could also become part of broader public health strategies. If you’re planning to travel, talk to your doctor about the typhoid conjugate vaccine.
  2. Practice Good Hygiene. Typhoid spreads through contaminated food and water. Simple practices like frequent handwashing and avoiding undercooked foods can reduce your risk.
  3. Support Global Vaccination Efforts. Pakistan has led the way by rolling out routine immunizations for typhoid. More countries are following suit, but these programs need global support. Advocating for and supporting these initiatives can make a difference.
  4. Push for New Research. The fight against antibiotic resistance requires investment in new drugs. Encourage lawmakers to prioritize funding for medical research and public health initiatives.

Antibiotic resistance isn’t just about typhoid; it’s a broader crisis affecting infections worldwide.

And while the numbers are sobering—antibiotic resistance already claims more lives than HIV/AIDS or malaria—we still have tools to fight back.

Vaccines, good hygiene, and better healthcare infrastructure are all critical. But they require action—by individuals, communities, and governments—to make a real impact.

Let’s use the lessons learned from COVID-19: Early prevention is better than scrambling to react once the problem is out of control. And in the case of typhoid, we have the opportunity to act now.

Sources:

Cassella, C. (2024, December 8). An Ancient Killer Is Rapidly Becoming Resistant to Antibiotics, Study Warns. ScienceAlert. https://www.sciencealert.com/an-ancient-killer-is-rapidly-becoming-resistant-to-antibiotics-study-warns

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